Faculty Profile  Faculty ProfileLast Modified Time: 10:47:21 AM Fri, 30 Jan 2015 
Dr. Douglas D. Root
 Contact Information
Dr. Douglas D. Root
Associate Professor-Biological Sciences
Contact address   1504 W. Mulberry, Denton, TX 76203     Office LocationLSCB, Room No.: 322 
Email  DROOT@UNT.EDU    Contact Number (940) 565-2683   
Graduate Faculty Membership Status: Full Membership -Permanent   
toggle toggle  Professional Preparation
 Degree Major/Thesis/Dissertation Institution Year
Doctor of Philosophy Molecular Biology/"Structural Determinants of Actomyosin Interactions and Protein Quantification by Copper Iodide Staining." UCLA 1992
Bachelor of Science Biological Sciences University of California, Irvine 1985
toggle toggle Courses Taught By Semester --- Organized Classes will be uploaded from THECB Data file
SemesterSubjectCourse NumberSectionCourse NameCalculated Semester Credit HoursSyllabus 
Spring 2015BIOC4550001Biochemistry II Download Syllabus
Spring 2014BIOC4550001Biochemistry II Download Syllabus
Spring 2013BIOC4550001Biochemistry II Download Syllabus
Spring 2012BIOC4550001Biochemistry II Download Syllabus
Spring 2011BIOC4550001Biochemistry II Download Syllabus
Spring 2010BIOC5550001Biochemistry II30 
Spring 2010BIOC4550001Biochemistry II135 
Fall 2011BIOC6630001Protein Structure and Function  
Fall 2010BIOL6200001Bioinstrumentation and Analytical Techniques84 
Fall 2009BIOC6630001Protein Structure and Function48 
toggle toggle Appointments
Duration (YYYY - YYYY or Present)RankDepartment / SchoolCollege / OfficeUniversity / Company
2002-PresentAssociate ProfessorBiological Sciences University of North Texas
1996-2002Assistant ProfessorBiological Sciences University of North Texas
1995Guest LecturerUsing the Internet for Biochemistry, Biological Fluorescence, and Radioactivity in the Life Sciences University of Texas at Austin
1993-1995MDA Postdoctoral Fellow  University of Texas at Austin
1992-1993Post-doctoral Researcher  University of Texas at Austin
1991Teaching Assistant for BiochemistryDept. Chem. and Biochem UCLA
1988-1991NIH Tumor Cell Biology Predoctoral Trainee Molecular Biology InstituteUCLA
1987-1988Graduate Student Researcher Molecular Biology InstituteUCLA
1985-1987Research TechnicianHarbor/UCLA Medical CenterResearch and Educational InstituteUCLA
toggle toggle Faculty Workload
Duration (YYYY - YYYY)Percentage TeachingPercentage ResearchPercentage Service
toggle toggle Publications
  Type  Publications per page   
2 3 4 5 6 7 8 9 10 Next>> 17>> 
  YearPublication  Type
Asymmetric Myosin Binding to the Thin Filament as Revealed by a Fluorescent Nanocircuit
Pilar Castro-Zena and Douglas D. Root
Archives of Biochemistry and Biophysics
Refereed(Peer reviewed) Journals
Demonstrating the uses of the novel Gravitational Force Spectrometer to stretch and measure fibrous proteins
James Dunn and Douglas D. Root
Refereed(Peer reviewed) Journals
“ Close Proximity of Myosin Loop 3 to Troponin Determined by Triangulation of Resonance Energy Transfer Distance Measurements,”
Patel, D. A.
Refereed(Peer reviewed) Journals
“Photoactivatable Quantum Dots in Super-Resolution 3D Microscopy of Myofibrils .”
Gopal, T., Luchowski, R., Akel, A., Gryczynski, Z., and Borejdo, J.
Biophys. J.
Abstracts and Proceedings
“Troponin/Tropomyosin Determines Myosin Target Zones Along the Thin Filament .”
Patel, D. and Jin, J.-P.
Biophys. J.
Abstracts and Proceedings
toggle toggle Editorships
Duration (YYYY - YYYY or Present)OrganizationPositionClassification
2012-PresentArchives of Biochemistry and BiophysicsEditorial Board Member 
2009-PresentCurrent Drug Discovery TechnologiesEditorial Board Member 
 Journal of Structural BiologyReviewer 
 Journal of Muscle Research & Cell MotilityReviewer 
 Journal of FluorescenceReviewer 
 Journal of Clinical Endocrinology & MetabolismReviewer 
 Journal of Chemical PhysicsReviewer 
 European Biophysics JournalReviewer 
 BMC Cell BiologyReviewer 
 Biophysical JournalReviewer 
toggle toggle Lectures/Symposia
1995Physiology & Biophysics seminarinvited seminarUniversity of Virginia
1991 invited seminarNIH/NHLBI
1991 invited seminarBoston Biomedical Research Institute
toggle toggle Presentations and Projects
  Presentations/Projects per page   
1  2 3 4 
Start DateEnd DatePresentation/Project
2009 2009 Invited presentation in the Texas Society for Microscopy Spring Meeting
2008 2008 Invited presentation in the TWU Biological Sciences Seminar Series
2008 2008 Invited lectures for UNTHSC Biochemistry
toggle toggle External Funding
 Performance PeriodTitleSponsorFundingRoleStatus
2009-2013Gravitational Force Spectroscopy of Single MyosinNSF$231,431Principal InvestigatorActive
2008 UNTHSC$19,750Principal InvestigatorCompleted
2006-2007 NSF MRI$270,000Co-PICompleted
2003-2005 NIH R01 Award$295,863Principal InvestigatorCompleted
2002-2003 American Heart Association, Texas Affiliate, Grant-in-Aid$124,000Principal InvestigatorCompleted
1997-2002 NIH FIRST Award$273,500Principal InvestigatorCompleted
1999-2000 NIH SBIR funded grant$37,500OtherCompleted
1997 American Heart Association, Texas Affiliate, Grant-in-Aid$88,000Principal InvestigatorCompleted
1996-1997 North Texas Research Laboratories$3,500OtherCompleted
1993-1994 Muscular Dystrophy Association Fellowship$57,000Principal InvestigatorCompleted
1988-1991 NIH Tumor Cell Biology Predoctoral Trainee$32,000OtherCompleted
0000Faculty Research Grants $40,100OtherCompleted
0000Junior Faculty Summer Research Fellowships $10,500OtherCompleted
0000UNT ExcellenceUNT$438,343OtherCompleted
toggle toggle Affiliations
Biophysical Society
American Association for the Advancement of Science
toggle toggle Teaching
Biochemistry (BIOC 4550)/Undergraduate

Biochemistry (BIOC 5550)/Graduate

Bioinstrumentation & Analytical Tech. (BIOL 6200)/Graduate

Protein Structure & Function (BIOC 6630)/Graduate

toggle toggle Mentoring/Advising
Duration (YYYY - YYYY or Present)Student NameClassificationTypeProject/Thesis/Dissertation
2009Amal AkelMaster of Science/Molecular BiologyGraduate Mentoring/Advising 
2009Kunal PanwarTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2009Ruby SunTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2009Spencer MoonTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2009Kathy WangTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2009James DunnMaster of Science/BiochemistryGraduate Mentoring/Advising 
2009Dipesh PatelDoctor of Philosophy/BiochemistryGraduate Mentoring/Advising“LRET-based Modeling of Troponin in the Presence of Myosin and Troponin/Tropomyosin Defining Myosin Binding Target Zones in the Reconstituted Thin Filament”
2007-2009Irene CaiTAMSUndergraduate Mentoring/AdvisingBarry M. Goldwater Scholar/Siemens-Westinghouse regional finalist/ TAMS summer research scholarship
2008Azhar AssadiTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2008Tejas GopalTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2008Ankoor KambhampatyTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2007Kim PatelTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2007Kokila MuthukumarTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2007Eric LockettBiologyUndergraduate Mentoring/Advising 
2007Chandana RaviKumarTAMSUndergraduate Mentoring/Advising 
2007Ravi GawalapuDoctor of Philosophy/BiochemistryGraduate Mentoring/Advising“Fluorescence labelling and computational analysis of the strut of myosin’s 50 kDa cleft”
2007Pilar CoffeeMaster of Science/BiochemistryGraduate Mentoring/Advising“Hindrance of the Myosin Power Stroke Posed by the Proximity to the Troponin Complex Identified Using a Novel LRET Fluorescent Nanocircuit”
2007regional finalistTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2006Stephanie LoboTAMSUndergraduate Mentoring/Advising 
2006Stacey MathewTAMSUndergraduate Mentoring/Advising 
2006Nirav BahktaTAMSUndergraduate Mentoring/Advising 
2006Preet GurusamyTAMSUndergraduate Mentoring/AdvisingTAMS summer research scholarship
2005Stephanie HsuTAMSUndergraduate Mentoring/Advising 
2005Steven PetscheBiology, TAMSUndergraduate Mentoring/Advising 
2005Zhiling ZhangDoctor of Philosophy/BiochemistryGraduate Mentoring/Advising“The structure and function of troponin T upon metal ion binding and the detection of nucleic acid sequence variations”
2004Carlos VaccaroMaster of Science/BiochemistryGraduate Mentoring/Advising“Use of Luminescence Energy Transfer Probes to Detect Genetic Variants”
2004Deepika GundapaneniMaster of Science/BiochemistryGraduate Mentoring/Advising“Studies on Actomyosin Crossbridge Flexibility Using a New Single Molecule Assay”
2004Zach ZhangBiology, TAMSUndergraduate Mentoring/AdvisingSiemens-Westinghouse Semifinalist/ Intel Science Talent Search Semifinalist/ TAMS summer research scholarship
2002Dipesh PatelBS BiochemistryUndergraduate Mentoring/Advising 
2002Keili PetermanBS BiologyUndergraduate Mentoring/Advising 
2002Todd WardBS BiochemistrUndergraduate Mentoring/Advising 
2001Lance KentBiologyUndergraduate Mentoring/AdvisingTAMS summer scholarship
2001Shaun StewartBS BiologyUndergraduate Mentoring/AdvisingBarry M. Goldwater Scholar/Siemens-Westinghouse regional finalist/Intel Science Talent Search semifinalist/TAMS summer scholarship
2000-2001Jin XuPost-Doc/BiochemistryGraduate Research 
2000Jin XuDoctor of PhilosophyGraduate Mentoring/Advising"Conformational Studies of Myosin and Actin with Calibrated Resonance Energy Transfer."
2000Park HyungukMaster of Science/BiochemistryGraduate Mentoring/Advising"Noncovalent Crosslinking of SH1 and SH2 in to Demonstrate the Flexibility of SH1-SH2 alpha-Helix"
2000Isabelle MoyaBS BiologyUndergraduate Mentoring/Advising 
1999Ken DakinBS Biology McNair ScholarUndergraduate Mentoring/Advising 
1999Carlos VaccaroBS BiochemistryUndergraduate Mentoring/Advising 
1998Hami TealBS Biochemistry McNair ScholarUndergraduate Mentoring/Advising 
1998Jason McInerneyBS BiochemistryUndergraduate Mentoring/Advising 
1997Ankur JainTAMSUndergraduate Mentoring/Advising 
1997Kevin ChiuTAMSUndergraduate Mentoring/Advising 
1997Carlos MorenoTAMSUndergraduate Mentoring/Advising 
toggle toggle Committees
Duration (YYYY - YYYY or Present)CommitteePositionClassification
2001-PresentMolecular Biology Program CommitteeChair in 2002, 2004, 2006 
1999-PresentUniversity Scholarship Committee  
2002-2007University Curriculum Committee  
2001-2004Elected CAS Undergraduate Curriculum Committee  
2002-2003Biochemistry Faculty Search Committeemember 
2000-2002Physiologist Faculty Search Committeemember 
toggle toggle Honors and Recognitions
YearTitleHonoring Organization
 Certificates of Recognition, Ronald E. McNair ProgramUNT
 International Master of ChessFIDE
 Graduated Cum Laude with HonorsUC Irvine
 Student Research AwardUC Irvine
 Silver MedalistWorld Youth Team Chess Championship, Argentina
 University of California Regents’ ScholarshipUniversity of California
 ValedictorianWalnut High School, CA, (500 students in class)
toggle toggle Professional Community Engagement
YearOrganizationRoleType of Service
2007-2008OCASTBiochemistry Review Panel, Chair in 2008 
2006-2007Laboratory Sciences Advocacy GroupConvener 
2005-2006CSRSpecial Emphasis Panel Member for R01 grants 
2004-2005NIH Program Project AwardsReview Panel Member 
2004-2008NIH R03 AwardsReview Panel Member 
2004NIH R21 AwardsReview Panel Member 
2004North West Cancer Research grant (Liverpool, UK)ad hoc reviewer 
2002Chemistry DepartmentInvited seminar "Spectroscopic and Computational Analysis of a Molecular Motor " for Chemistry Department Seminar 
2002Ronald E. McNair scholarship programparticipantparticipation in the grant renewal
2002- Department P&T A Chair, 2002-2005 
2002- Department PAC 
2002NIH R01 grantad hoc CSR Study Section reviewer 
1999-2006Faculty Sponsor UNT Chess Club  
1999Materials Science Department SeminarInvited seminar "Molecular Motors in Nanotechnology" 
1999 Library Representative 
1998Ronald E. McNair scholarship programparticipantparticipation in the grant renewal
1998-2002 Physical Plant Committee representative 
1998-2000 organizer of a Division website 
1998UNTHSCAwards Judge for research appreciation day 
1998Intel ISEFGrand Awards Judge for Biochemistry 
1997-2004 presentations (10) in the Vistas in Biochemistry Seminar Series 
1996-UNTReviewerFaculty Research Grant Applications
1996- Biochemistry Division Secretary 
1996- hosted speakers (10) for the Departmental Seminar Series 
1995- Presented Biology Departmental Seminars (3) 
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